After missing the first wave of GLP-1 blockbusters, Roche is investing billions in a new generation of obesity treatments. With Novo Nordisk and Eli Lilly dominating the market, can the Swiss pharma giant still find a foothold? In early March, Swiss pharma giant Roche put out some good news about the obesity drug candidate Petrelintide it’s developing with Danish biotech Zealand Pharma. In a phase II trial, the medication, injected once a week, met its primary endpoint of statistically significant weight loss. Participants shed on average 10.7% of their body weight and sustained the loss to 42 weeks with only mild side-effects. But investors weren’t impressed. Shares of Zealand Pharma dropped by a record 35% the day after the announcement, while Roche fell around 3%. In today’s world of obesity drugs, 10.7% weight loss is hardly remarkable. Users of Eli Lilly’s Zepbound (tirzepatide) and Novo Nordisk’s Wegovy (semaglutide) have reported losing 15-20%. In clinical trials of Zepbound ...
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Can Swiss pharma giant Roche reshape the obesity market?
Published on April 2, 2026
Permanent link to this article: https://snbchf.com/2026/04/swiss-pharma-giant-roche-reshape-obesity-market/
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